BACTERIOGICAL PROFILE OF CRITICALLY ILL PATIENTS IN INTENSIVE CARE UNIT IN BANGALORE

Objective: Intensive care units (ICUs) are considered as the epicentre of infections due to its vulnerable conditions for development, amplification, and dissemination drug-resistant microorganisms. Furthermore, use inappropriate or incorrect antibiotics is also closely related development spread Hence, present study was conducted in a private hospital South Bangalore, evaluate spectrum micro organisms isolated from clinical samples patients admitted ICU their antimicrobial susceptibility pattern. Methods: This observational on critically ill medical ICUs south Karnataka, India. The designed include all with age 18 years older, more than 48 h having at least two signs SIRS. Depending suspicion, such pus, blood, urine, body fluids, respiratory specimen were collected. collected first subjected gram staining then inoculated blood agar MacConkey plates taking proper aseptic precautions. Antimicrobial sensitivity patterns respective studied Mueller Hinton media by Kirby Bauer’s disk diffusion method. Results: A total 665 received microbiology laboratory out which 60% showed significant microbial growth. most predominant isolates Gram-negative 72.68% Gram-positive seen 27.3%. Sample-wise distribution positive culture done. Pus 33%, 26%, urine 20%, 15%, fluids 6%. Majority susceptible amikacin, followed piperacillin/tazobactum, cefeperazone/salbactum imipenem high resistance rates ampicillin, amoxy clav noted. Most Staphylococcus aureus sensitive linezolid, vancomycin, pipercillin/tazobactum, cefeperazone/salbactum. Conclusion: prevalence aerobic bacteria ICUs. identified both be responsible causing stream infections. There should continuous surveillance data along pattern routine baseline resistance, stringent infection policy, implementation need hour stop reduce drug resistance.